Open access
Sep 2026
An Engineered HR1‐Stem Helix‐HR2 Trimeric Platform for Developing Broad‐Spectrum Coronavirus Vaccines
RHS is established as a generalizable strategy for overcoming viral immune evasion and advancing next‐generation vaccine design, and is readily adaptable to antigens from SARS‐CoV and MERS‐CoV, underscoring its versatility for pan‐coronavirus vaccine development.
Xi-Kui Sun, Junhao Fan, Xiaolu Xie et al.
· Advancement of science · 0 citations