B-219 High seroprevalence but low frequency of intrathecal anti-Epstein-Barr virus IgG suggests a unique role of Epstein-Barr virus infection in multiple sclerosis
Multiple sclerosis (MS) is strongly associated with high anti-Epstein-Barr virus (EBV) IgG seroprevalence. Many patients with MS have an intrathecal production of antiviral antibodies, which can be detected by elevated antibody indices (AI) [1,2]. In fact, the detection of intrathecal antibodies against measles,...