Open access
Oct 2026
Multi-omic profiling of 85 iPSC lines from familial dementia reveals cellular diversity and regulators of organoid development.
Systematic molecular characterization of human induced pluripotent stem cell (iPSC) lines carrying disease-associated mutations is needed to distinguish disease-related biology from variation in cell state, genomic integrity, and genome-editing history, yet such systematic characterization is uncommon. Here, we profile...
Le Qi, T. Bertucci, Susan Borden et al.
· Neuron · 0 citations