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Author

Kathryn E. Yost

2 papers indexed here

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Open access Oct 2026

Comprehensive lineage tracing maps the landscape of cell fate decisions in mouse embryogenesis.

A comprehensive cell fate map of mammalian embryogenesis has remained out of reach given the scale, cellular diversity, and non-deterministic nature of development in utero. Here, we use PEtracer to continuously install heritable genetic marks as development progresses, reconstructing lineage trees that resolve ∼75% of...

William N. Colgan, Luke W. Koblan, JoAnne Villagrana et al. · 2 citations
Open access Sep 2026

Spatiotemporal lineage tracing reveals the dynamic spatial architecture of tumor growth and metastasis

Tumor progression is driven by dynamic interactions between cancer cells and their surrounding microenvironment. Here we integrate high-resolution spatial transcriptomics and evolving lineage-tracing technologies to elucidate how tumor expansion, plasticity and metastasis co-evolve with microenvironmental remodeling in...

Matthew G. Jones, Da-Wei Sun, Kyung Hoi (Joseph) Min et al. · 0 citations

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