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Author

Kathrin Tan

1 paper indexed here

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Open access Oct 2026

Discovery of Potent and Non-cytotoxic HDAC3-Selective Degraders Featuring a Propyl Hydrazide Zinc-Binding Group

Novel class I HDAC degraders derived from the HDAC3-preferential inhibitor FL-007 showed no cytotoxicity up to 100 μM in both cancerous and non-cancerous cell lines, and resulted in moderate chemosensitization of cisplatin-resistant Cal27CisR cells.

Stephan Lepper, Lukas Biermann, Fabian B. Kraft et al. · 0 citations

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