Aspartic Protease Inhibition as an Anti-Malarial Strategy
Due to rising drug resistance, novel therapeutics are needed to combat the causative agent of malaria, Plasmodium spp.. Aspartic protease inhibition has emerged as a promising frontier for anti-malarial development as P. falciparum expresses five essential aspartic proteases in its symptomatic erythrocytic stages. Thes...