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Katherine E. Brechun

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Open access Aug 2026

Antibiotic-free maintenance of multiple plasmids in Escherichia coli using conditional complementation

A key sustainability concern in biotechnology is the heavy reliance on antibiotics and antibiotic resistance genes (ARGs) for plasmid selection and maintenance. This is leading to increasing regulatory pressure to develop antibiotic-free biomanufacturing processes. Currently, there are limited options enabling antibi...

Katherine E. Brechun, Marion Förschle, Marlen Schmidt et al. · 0 citations

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