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Katharina Bergauer

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Open access Aug 2026

BARe-seq enables high-throughput dissection of cis-regulatory control of transcriptional bursting

Transcriptional bursts determine RNA output through two kinetic parameters: burst size and burst frequency. How cis-regulatory DNA encodes these kinetic parameters remains unclear, in part because existing approaches do not combine scalable sequence perturbation with allele-resolved burst inference. Here, we developed...

Franziska K. Lorbeer, Reyna Edith Rosales Alvarez, Katharina Bergauer et al. · 0 citations

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