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Author

Kate Marinchev

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Open access Sep 2026

Therapy-persistent leukemia is selectively vulnerable to SLC23A1 restoration via targeting KHSRP.

Acute myeloid leukemia (AML) is prone to relapse driven by therapy-persistent residual cells. To discover specific vulnerabilities in this population, we performed genome-wide CRISPR interference screens in leukemia cells treated with multiple agents. KHSRP was the top hit, whose depletion sensitized AML cells to thera...

Qing-Yu Luo, Karley S. Whalen, Xiao-Wei Wu et al. · 0 citations

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