Structural Plasticity and Ligand Promiscuity of CYP3A4 Revealed by Cryo-EM
The routine use of cryo-EM to resolve CYP3A4 ligand-bound complexes will provide the ground truth data needed to make predictive models of drug metabolism useful in practice.
Anna K. Orta, Jan-Hannes Schäfer, G. Correy et al.
· bioRxiv · 0 citations