Nanoplastics and thermal stress induce synergistic toxicity in marine medaka (Oryzias melastigma) through epithelial barrier damage, immuno-metabolic dysregulation, and cancer-associated transcriptional signatures.
Marine organisms are increasingly exposed to nanoplastics (NPs) and rising temperatures due to climate change, yet their combined effects remain poorly understood. Here, we investigated the interactive toxicity of polystyrene nanoplastics (PS-NPs, 80 nm) and elevated temperature (32 °C vs 25 °C) in marine medaka larvae...