Open access
Oct 2026
Mapping of Pre-Existing Humoral Immunity to AAV and Natural AAV Capsid Presence in Human Tissues: Observations from a Polish Surgical Cohort
Vectors based on adeno-associated viruses (AAVs) are widely used as a delivery system in gene therapy. However, preexisting immunity against AAV remains a major limitation. This study examines the prevalence of AAV genomes and anti-AAV2 immunity in a Polish cohort of adult patients undergoing planned surgical intervent...
A. Majewska, Klara Weronika Siejda, M. Kowalec et al.
· Viruses · 0 citations