Open access
Aug 2026
Plectin promotes an aggressive phenotype and represses cytotoxic T cell activity in pancreatic cancer
Plectin is identified as a biomarker of aggressive disease in PDAC, with high plectin expression associated with decreased T cell infiltration, and anti-CSP treatment reinstates antitumor immunity and decreases tumor volume in vivo.
Cody L. Wolf, Roxanne K. Ruiz, Sokchea Khou et al.
· Frontiers in Immunology · 0 citations