Open access
Oct 2026
Integration of polygenic risk with single cell methylation data using met-scDRS
Abstract Motivation Although large scale genome-wide association studies (GWAS) have identified many risk variants for psychiatric traits their functional implication remain largely unknown. One potential mechanism for their risk is through cellular context-dependent epigenetics such as methylation. Previous methodolog...
Xin-Zhe Li, Zhuo-Zheng Shi, Kang-Cheng Hou et al.
· Bioinformatics · 0 citations