Kamil Slowikowski

A Community-Driven Single-Cell PBMC Reference Integrating Landmark Datasets Spanning Health and Disease

Maternal and fetal cellular programs orchestrate pregnancy complications and placental tolerance

The placenta is a transient organ that orchestrates maternal-fetal interactions essential for healthy pregnancy, yet the multicellular principles governing placental dysfunction remain poorly understood. Here, we present a multimodal single-cell atlas of the human placenta, profiling over 1.2 million cells from 68 dono...

A multimodal atlas of COVID-19 severity identifies hallmarks of dysregulated immunity 2258066

It is shown that myeloid-derived suppressor cells (MDSCs) act as a key immunologic pivot point in severe COVID-19, and this multimodal and high-dimensional dataset with curated clinical metadata provides a foundational and clinically relevant resource for modeling host immune response biology in health and disease.