Open access
Aug 2026
Distinct regulation of Wnt signaling and EPZ5676 governs human UiPSM reprogramming via the CDX2/T/TBX6 core axis
It is shown that Wnt/β-catenin signaling coordinates UiPSM reprogramming and maintenance via the CDX2/T/TBX6 axis, which offers new mechanistic understanding of human mesoderm lineage specification and somatic cell reprogramming.
Kaipeng Wang, Xingnan Huang, Huiru Gao et al.
· Cell Regeneration · 0 citations