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Kai-Wen Li

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Open access Sep 2026

Assessment of elemental decomposition algorithms for particle therapy dose monitoring using positron emission tomography and prompt-gamma imaging

Objective. Accurate dose verification remains a major challenge in particle therapy. Dose monitoring methods such as positron emission tomography (PET) and prompt-gamma (PG) imaging are highly sensitive to uncertainties in tissue composition derived from CT, which can be improved by dual-energy CT (DECT)-based material...

Yan Li, Wei-Guang Li, Xin-Yu Hu et al. · 0 citations
Open access Aug 2026

A physics-informed decomposition network for carbon ion radiotherapy dose monitoring: a proof-of-concept study

Objective. In-beam positron emission tomography (PET) provides a promising strategy for dose monitoring in carbon ion radiotherapy (CIRT), but accurate dose prediction remains difficult due to the complex, nonlinear relationship between positron-emitter activity and physical dose deposition. This proof-of-concept study...

Xin-Yu Hu, Yan Li, Wei-Guang Li et al. · 0 citations

Physics in Medicine & Biology

The proposed framework improves dose prediction while incorporating physically meaningful priors into the learning process, offering a promising basis for PET-based dose-monitoring model development in CIRT.

Yan Li, Wei-Guang Li, Xin-Yu Hu et al. · 0 citations

Physics in Medicine & Biology

The proposed surface-aware DDIM-RePaint framework provided an accurate and efficient approach for longitudinal CBCT FOV extension, potentially facilitating patient setup and ART planning without extra imaging dose and hardware upgrade.

Jueye Zhang, Qijian Lu, Ya-Si Zhang et al. · 0 citations

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