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Open access Oct 2026

Predictors of therapeutic response to left bundle branch area pacing and atrioventricular node ablation in patients with atrial fibrillation and heart failure

Left bundle branch area pacing (LBBAP) with atrioventricular node (AVN) ablation has emerged as a promising therapy for patients with atrial fibrillation (AF) and symptomatic heart failure (HF). However, it remains unclear which patients are likely responders and which may derive limited benefit. This stud...

Li-Shui Shen, H. Li, K. Tang et al. · 0 citations
Open access Aug 2026

Single-nucleus transcriptomic analysis identifies a putative Purkinje fiber-associated remodeling program after myocardial infarction

A secondary analysis of the human myocardial infarction atlas prioritizes a putative PF-associated transcriptional remodeling program for follow-up and uses TsPF to denote transitional PFs, a study-specific transitional Purkinje fiber subpopulation resolved by cardiomyocyte re-clustering and characterized by an interme...

Pei-Ran Song, Ze-Min Kang, Hai-Yan Hou et al. · 0 citations

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