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Author

Kai-Jia Hu

2 papers indexed here

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Review Open access Oct 2026

Lipid droplet–mitochondria crosstalk in osteoarthritis: linking lipid routing to metabolic mismatch

Osteoarthritis (OA) is a whole-joint disease characterized by metabolic reprogramming beyond structural degeneration. Increasing evidence indicates that lipid droplets (LDs) regulate lipid storage, mobilization and intracellular lipid routing, while alterations in mitochondrial metabolism determine the capacity of chon...

Gang Meng, Rui-Jie Hou, Ping Dong et al. · 0 citations
Review Open access Aug 2026

Targeting Tryptophan Metabolism in Cardiovascular Disease: From Immune-metabolic Crosstalk to Precision Therapy.

Host-microbiota co-metabolism of tryptophan is increasingly recognized as a critical nexus linking diet, gut microbiota, immune function, serving as a core regulatory network governing cardiovascular function and systemic homeostasis. Its catabolism in vivo mainly proceeds through three distinct pathways: the kynurenin...

Hao-Yuan Hu, Wei Guo, Xin-Yi Li et al. · 0 citations

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