Kai-Chong Jiang

Luteolin potentiates antibiotic activity against multidrug-resistant Pseudomonas aeruginosa and modulates efflux-associated resistance and biofilm-associated phenotypes

Multidrug-resistant Pseudomonas aeruginosa is a WHO critical-priority pathogen whose recalcitrance is driven largely by efflux pump overexpression and biofilm formation, two mechanisms rarely addressed by a single agent. Here we evaluated whether luteolin, a plant-derived flavone, could potentiate conventional an...