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Author

K. Yoshimatsu

2 papers indexed here

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Open access Oct 2026

Geriatric Assessment-Based Stratification to Evaluate Treatment Intensity, Quality of Life, and Survival in Older Patients With Metastatic Colorectal Cancer: Protocol for a Prospective Observational Study.

BACKGROUND Older patients with metastatic colorectal cancer (mCRC) are a heterogeneous population with wide variability in functional status, frailty, cognition, nutritional reserve, and comorbidity burden. Treatment decisions are often guided primarily by chronological age and performance status, which may not adequat...

Takako Hiramatsu, Izumi Okazaki, Kyoko Hosokawa et al. · 0 citations
Open access Aug 2026

Stroma-Dominant Colorectal Cancer Harbors CAF-Rich Spatial Architecture and EMT-Associated Cancer Cell Plasticity Detectable After Dissemination

Stroma-dominant CRC is characterized as a spatially organized ecosystem in which a CAF-rich compartment is associated with stress-adapted cancer cell programs, and its poor prognosis may involve not only stromal abundance but also a morphology-associated cancer cell state detectable after dissemination.

S. Kitagawa, N. Mimura, Hironobu Kambara et al. · 0 citations

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