Syringotoxin Biosynthetic Gene Cluster Required for Antiamoebal Defense in Pseudomonas syringae.
Syringotoxins are chlorinated cyclic lipopeptides from Pseudomonas syringae that were structurally characterized more than three decades ago. The corresponding biosynthetic gene cluster required for their production, however, has not been experimentally assigned. Based on targeted genetics, metabolite profiling, and st...