Bridging Neural Scales in Epilepsy Research for Human Health: A Review and Conceptual Framework for Multiscale Computational Modeling
Epilepsy is a neurological disorder caused by recurrent seizures due to a hypersynchronous activity of neurons that can spread out to larger networks. How this activity on smaller scales transfers to higher levels is hard to capture computationally. Previous works usually focus on either microcircuit level biophysics...