Although 18F-FDG PET is commonly used in the differential diagnosis of cognitive decline, synaptic vesicle glycoprotein 2A PET may offer a more direct assessment of synaptic integrity and address limitations associated with 18F-FDG, such as sensitivity to sensory stimuli and glycemic variations. In this study, a head-t...
Charles Carron, L. Boeckxstaens, Louis Degryse et al.· Journal of Nuclear Medicine· 0 citations
Abstract Molecular connectivity analysis with positron emission tomography (PET) imaging offers a promising approach for characterising brain network alterations in neurodegenerative disorders. In this study, we introduce Wasserstein distance (WD) as an alternative to Kullback–Leibler divergence similarity estimation (...
Chun-Meng Tang, Joke de Vocht, P. van Damme et al.· Imaging neuroscience· 0 citations
Alzheimer’s disease (AD) pathology is increasingly recognized to manifest in the retina, offering a non-invasive window for early biomarker discovery. This proof-of-concept study investigated whether multimodal retinal imaging—hyperspectral imaging (HSI), optical coherence tomography (OCT), and color fundus photography...
Michiel Ghesquiere, Eirini Christinaki, Sophie Lemmens et al.· Bioengineering· 0 citations
Whether a supervised machine learning technique, support vector machines (SVM), can replicate the assignments made by visual readers blind to the clinical diagnosis, which image components have highest diagnostic value according to SVM and how 18 F-flutemetamol-based classification using SVM relates to structural MRI-bas...
R. Vandenberghe, N. Nelissen, E. Salmon et al.· 0 citations
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