Circulating angiopoietin-like protein 3 levels and subsequent cardiovascular outcomes in patients with coronary artery disease
Angiopoietin-like protein 3 (ANGPTL3) is a secretory glycoprotein mainly expressed in the liver, which regulates metabolism of triglyceride-rich lipoproteins. Pathophysiologically, ANGPTL3 inhibits lipoprotein lipase activity and endothelial lipase activity, which diminishes the clearance of triglyceride-rich lip...