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Review Aug 2026

Beyond Survival: Prospective Longitudinal Insights into Health-related Quality of Life After Hepatectomy for High-risk Colorectal Liver Metastases.

OBJECTIVE Describe the long-term health-related quality of life (HR-QoL) after curative-intent hepatectomy for high-risk colorectal liver metastases (CRLM). METHODS This prospective study enrolled patients with resectable CRLM with clinical risk score ≥3. European Organization for Research and Treatment of Cancer QLQ...

Ankur P. Choubey, J. Leal, C. White et al. · 0 citations
Open access Sep 2026

Neoantigen-reactive CD8+ T cell engagement marks exceptional survivors of pancreatic cancer

Pancreatic cancer (PC) is largely refractory to immune checkpoint blockade (ICB), although homologous recombination-deficient (HRD) tumors may derive benefit. In the POLAR trial of maintenance pembrolizumab plus olaparib after platinum-based chemotherapy for metastatic PC, responses remained heterogeneous. To define de...

M. Hilmi, J. Schoenfeld, Wilson H. McKerrow et al. · 0 citations

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