Author

K. Santhoshkumar

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Review Open access Aug 2026

DNA hydroxymethylation-mediated epigenetic modifications in alcohol use disorder

Findings of TETs-mediated 5-hydroxymethylation in AUD are summarized and the key challenges and research gaps in understanding the underlying mechanisms of TETs/5hmC-mediated epigenetic modification in AUD are highlighted.

Sampath Raghul Kannan, K. Santhoshkumar, R. Tamizhselvi · Frontiers in Aging Neuroscie... · 0 citations

Open access Aug 2026

Genomic exploration and in silico prioritization of putative COX-2-targeting metabolites from Streptomyces sp. VITGV156 (MCC 4965)

Introduction Streptomyces species represent an important source of bioactive natural products, yet systematic genome-guided prioritization of metabolites targeting cyclooxygenase-2 (COX-2/PTGS2) remains limited. This study aimed to investigate the biosynthetic potential of Streptomyces sp. VITGV156 (MCC 4965) using an...

Veilumuthu Pattapulavar, Saranyadevi Subburaj, Sathiyabama Ramanujam et al. · Frontiers in Bioinformatics · 0 citations