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Author

K. Nogami

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Jul 2026

Extended Half-Life Recombinant Factor VIII Conjugated with Modifying Substances Does Not Affect Fibrin Clot Formation or Stability in Haemophilia A Blood Samples.

Direct modification by PEGylation or IgG-Fc fusion to impart EHL characteristics preserves the functional properties of native FVIII, suggesting that PEGylation or Fc fusion do not impair its functional properties related to fibrin clot formation and stability.

N. Shimonishi, K. Nogami · 0 citations

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