Author

K. Nakhate

2 papers indexed here

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Oct 2026

Plumbagin reduces anger-like phenotype in rats by suppressing nitric oxide signaling and enhancing serotonergic transmission in the central nucleus of the amygdala.

Intermittent explosive disorder (IED) is characterized by impulsive outbursts of anger and violent behavior, involving dysregulation of limbic circuits underlying emotional and behavioral control. Neuronal nitric oxide synthase (nNOS)-derived nitric oxide may modulate serotonergic neurotransmission involved in anger re...

Kamini R. Shirasath, Dipak K. Sahare, Akash M. Waghade et al. · Brain Research · 0 citations

Aug 2026

Memantine modulates TRPM3-associated glutamatergic signaling via vGLUT2 in a mouse model of obsessive-compulsive disorder.

Findings support a novel TRPM3-vGLUT2-NMDA signaling axis in OCD and suggest memantine and primidone as promising candidates for targeted, mechanism-based therapy.

Prerana V Chaudhari, Sanjay N. Awathale, Sachin R. Ahire et al. · European Journal of Pharmaco... · 0 citations