Author

K. N. Faber

2 papers indexed here

We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.

Not the right person? Other researchers publish under this name.

Open access Oct 2026

Genome-wide analysis of genetic modifiers of Crohn’s disease and ulcerative colitis risk in response to tobacco smoking

Summary Background Gene-environment interactions (GxE) are fundamental for understanding the mechanisms of human diseases. Tobacco smoking is of particular interest for Inflammatory bowel disease (IBD), as it worsens Crohn’s disease (CD) but protects against ulcerative colitis (UC). Here, we systematically examined the...

Jing-Jing Bai, R. Gacesa, J. Björk et al. · EBioMedicine · 0 citations

Aug 2026

Upadacitinib effectively suppresses IL13RA2 expression in primary human intestinal fibroblasts derived from Crohn's disease tissue.

Results reveal that CD-derived phIFs show marked heterogeneity in basal IL13RA2 expression, which is strongly induced by IL13 and associated with JAK1-STAT6 pathway activation, both of which are effectively suppressed by upadacitinib.

Li Wang, Rui-Bin Wu, S. de Jong et al. · Biochemical Pharmacology · 0 citations