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K. Morishima

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#protein folding Oct 2026

Efficient production of recombinant human serum albumin in Escherichia coli via oxidative folding mediated by the a domain of protein disulfide isomerase.

It is demonstrated that PDI(a)-mediated cis-fusion enables high-yield production of structurally native-like and functionally competent HSA in the bacterial cytosol and provides a practical platform for producing complex disulfide-rich proteins in E. coli.

R. Urade, Yuki Yamaguchi, K. Morishima et al. · 0 citations

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