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Author

K. Moremen

3 papers indexed here

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Open access Oct 2026

Identification of glycosyltransferases that synthesize pectin heteroglycan block polymers and a structural motif required for their activity

Pectin is a family of plant cell wall complex polysaccharides and proteoglycans comprised of the glycan domains homogalacturonan (HG), rhamnogalacturonan I (RG-I), and the substituted HGs rhamnogalacturonan II (RG-II), xylogalacturonan and apiogalacturonan. The number, type, and arrangement of the pectic domains in dif...

Clifford T. Okoye, Robert A. Amos, Chin-Ling Huang et al. · 0 citations
Review Open access Aug 2026

Role of EXT Family Enzymes in Heparan Sulfate Biosynthesis.

Heparan sulfate (HS) proteoglycans are essential regulators of cell signaling, development, and extracellular matrix organization. Central to the HS biosynthesis pathway is the exostosin family of enzymes that control commitment to HS assembly and catalyze formation of the polymer backbone in the Golgi apparatus. Recen...

Digantkumar G Chapla, K. Moremen · 0 citations
Open access Aug 2026

Pectin O-3 deacetylation by Arabidopsis thaliana pectin acetylesterase 11 is important for sequential homogalacturonan degradation.

Pectin is a complex plant cell wall polysaccharide whose galacturonic acid residues can be acetylated at O-2 and/or O-3 positions. The degree of acetylation is regulated by pectin acetyl esterase (PAE, EC 3.1.1.6). However, the structure and function of plant PAEs is unclear, impairing our understanding of the role of...

Juliette Chislard, Liang Zhang, Romain Roulard et al. · 0 citations

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