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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

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K. Mechtler

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Open access Oct 2026

Making the Impossible Possible: Uniting TMT and DIA for Scalable Low-Input-Proteomics

Isobaric multiplexing using tandem mass tags (TMT) and data-independent acquisition (DIA) are two powerful techniques in quantitative proteomics, each offering distinct advantages. Combining these strategies provides synergistic benefits for low-input applications such as single-cell proteomics (SCP). However, integrat...

Tim Thierer, M. Birklbauer, Viktoria Dorfer et al. · 0 citations
#protein folding Open access Sep 2026

Pushing the limits of single-cell proteomics to investigate bacterial heterogeneity using bacSCP

Single-cell proteomics (SCP) has emerged as a powerful approach to quantify protein expression variability at cellular resolution, yet most state-of-the-art workflows are tailored to eukaryotic cells with only one study exploring how single bacteria can be analyzed by mass spectrometry. Here, we established bacSCP, a p...

Julia Leodolter, Tim Thierer, K. Mechtler et al. · 0 citations

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