Author

Kui-Ying Ma

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Review Open access Jul 2026

Base editing for precision therapeutics.

Key remaining challenges include bystander editing within the activity window, residual off-target DNA and RNA editing, delivery constraints, delivery constraints, immunogenicity, and the need for durable long-term safety evidence across relevant cell types and disease contexts.

Moksada Regmi, K. Ma, Changhao Bi et al. · Cell Genomics · 0 citations