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K. M

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Aug 2026

Optimized Lamotrigine-Loaded Polymeric Nanoparticles for Enhanced Drug Delivery: A Box-Behnken Design Approach with Integrated In Vivo Evaluation

Lamotrigine-loaded chitosan-sodium alginate polymeric nanoparticle system optimized by BoxBehnken Design demonstrated improved release control, enhanced pharmacokinetic parameters, and superior anticonvulsant activity in vivo, supporting their potential as a sustained-release system for epilepsy management.

D. R, J. B., K. M et al. · 0 citations

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