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Open access Sep 2026

Nutrient deprivation enhances the cytotoxic effects of a sulfonamide-chalcone hybrid in PC-3 prostate cancer cells.

Hybrid molecules integrating different pharmacophoric motifs have emerged as a promising strategy in anticancer drug discovery. In this study, we report for the first time the biological effects of a sulfonamide-chalcone hybrid in the PC-3 prostate cancer cell line under standard culture conditions and nutrient depriva...

G. S. de Araújo, R. E. de Sá, Stéphanie Aguiar de Negreiros Matos Silva et al. · 0 citations

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