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Author

K. Kinoshita

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Open access Sep 2026

Seafood and polyunsaturated fatty acid intake and age-related hearing loss: a cross-sectional study conducted in Japan

Background Age-related hearing loss (ARHL) is a common condition associated with dementia, social isolation, and reduced quality of life. N-3 polyunsaturated fatty acids (N-3 PUFAs), mainly derived from seafood, have been hypothesized to protect against ARHL through anti-inflammatory and antioxidant effects. However, e...

Jun Suzuki, Hiroki Tozuka, Hiyori Takahashi et al. · 0 citations
Open access Sep 2026

Inter-domain distance analysis reveals conformational changes in the Keap1-Nrf2 stress sensor system

The Keap1-Nrf2 system plays a central role in cellular defense against oxidative stress. Structural information on full-length Keap1 is essential for understanding the molecular basis of this regulation. However, its overall architecture has remained elusive due to pronounced conformational flexibility. In this study,...

Ritsumi Saito, Takeshi Kawabata, S. Yamashita et al. · 0 citations

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