Review
Open access
Jul 2026
Safeguarding the development of offspring: the role of genetic integrity of the maternal germline.
The role of maternal effect genes (MEGs) in orchestrating early zygotic development is explored, detailing their functions in epigenetic regulation, mitochondrial dynamics, DNA repair, and cell division, and the first comprehensive catalogue of associated diseases is presented.
Xuebi Cai, K. Hutt, Amy L. Winship et al.
· Endocrine reviews · 0 citations