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K. Hosomi

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2 papers indexed here

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Open access Sep 2026

Multilayered Prioritization of Graph Attention Autoencoder–Derived Drug Repurposing Candidates for COVID-19

By integrating GATE-based prediction, real-world evidence, and phenome-level pathway profiling, this study enabled multidimensional candidate prioritization that single analytical methods do not provide and offers a generalizable strategy for rapid candidate identification during pandemics and diseases with unmet thera...

Yusuke Nakayama, S. Tsuji, Koji Yamamoto et al. · 0 citations
Sep 2026

Pharmacotherapy of heart failure: Impact of the 2021 guideline update on guideline-directed medical therapy assessed using a Japanese employee health insurance claims database.

The 2021 guideline update was associated with increased use of sacubitril/valsartan and dapagliflozin, resulting in greater overall GDMT intensity, however, these findings are limited to data from 2021, and further long-term studies are needed to evaluate trends in GDMT utilization.

T. Uno, K. Hosomi, S. Yokoyama · 0 citations

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