K. Fassbender

Ex vivo activation unmasks a sex-convergent, exhaustion-associated CD8+ T cell expansion in Parkinson’s disease

Parkinson’s disease (PD) affects an estimated 6.4 million men and 5.3 million women worldwide, and still lacks a validated peripheral biomarker. Brain tissue is inaccessible in living patients, making peripheral blood an attractive alternative, but existing studies have profiled immune cells almost exclusively as stati...