Aim: Age-related macular degeneration (AMD) is a leading cause of vision loss in older adults, with genetic factors strongly influencing onset and progression. This study aimed to analyse GWAS data to identify AMD-associated genetic variants and explore their biological and regulatory significance.
Methodology: Public...
Loya Geeta Anusha, N. Uday Kumar, E. V. Ravikanth et al.· Journal of environmental bio...· 0 citations
This integrative analysis enhances knowledge on the genetic and molecular architecture of bipolar disorder, reinforcing its polygenic nature and implicating mitochondrial dysfunction, immune dysregulation, and neurotransmitter imbalances.
J. Timmapuram, G. Baby Shalini, T. Poojasree et al.· Journal of environmental bio...· 0 citations
Novel insights are revealed into CHD genetics, confirming known loci such as 9p21.3 (CDKN2B-AS1), COL4A2 and PHACTR1, while uncovering their broader functional roles in vascular remodelling, inflammation, and lipid metabolism.
T. Amulya, S. Vadlamudi, K. Farzia et al.· Journal of environmental bio...· 0 citations
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