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K. Drickamer

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Open access Oct 2026

Glycan-mediated binding to collagen by a C-type lectin-like domain of the endocytic receptor Endo180 / uPARAP.

The primary role of the multidomain endocytic receptor designated Endo180 or uPARAP (urokinase-plasminogen activator receptor associated protein) is to facilitate internalization of collagen for lysosomal degradation during matrix remodeling in tissues. However, Endo180 interacts both with collagen and sugars and the r...

K. Drickamer, S. A. F. Jégouzo, H. Feinberg et al. · 0 citations

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