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Open access Oct 2026

Revisiting colchicine pharmacology: structural and pharmacokinetic insights into GLP-1 receptor engagement

Colchicine is a long-established anti-inflammatory agent primarily recognized for its microtubule-disrupting properties. Beyond its classical mechanism of action, potential interactions with alternative molecular targets remain incompletely understood. Given the growing relevance of glucagon-like peptide-1 receptor (GL...

K. Buran · 0 citations
Open access Oct 2026

Synthesis, Biological Evaluation, Molecular Docking and DFT Studies of Electronically Tuned Benzylidene-Based Schiff Bases

Inspired by the medicinally relevant stilbene scaffold, a series of six electronically tuned benzylidene-based Schiff base derivatives were designed, synthesized, and characterized by FT-IR, 1H NMR, 13C NMR, and ESI-MS analyses. The biological properties of the synthesized compounds were investigated through antioxidan...

K. Buran, E. Yıldırım, Nazmiye Öner et al. · 0 citations

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