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Open access Aug 2026

Cryo-EM structure of Escherichia coli HPII catalase serendipitously co-purified with a recombinant adhesin construct.

Catalases are key antioxidant enzymes that protect aerobic organisms from reactive oxygen species generated through metabolic activities and host immune responses. In Escherichia coli, the monofunctional HPII catalase (encoded by katE) forms a stable tetrameric enzyme that contributes to oxidative stress resistance. Du...

J. Iarocci, Max Song, Julie Nadeau et al. · 0 citations
Open access Sep 2026

SPEF1 mediates assembly of central pair microtubule complexes in cilia of Tetrahymena.

SPEF1 is a conserved calponin-homology domain protein that decorates the seam of central pair microtubules in the distal segment of motile cilia. Here, we show that in the ciliate Tetrahymena, loss of SPEF1 disrupts the central pair throughout the middle segment, which comprises most of the cilium, producing gaps in th...

Mayukh Guha, Krishna Kumar Vasudevan, Yu-Yang Jiang et al. · 0 citations

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