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K. Bakheit

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Open access Oct 2026

Association of MTHFR C677T and A1298C Polymorphisms with Preeclampsia among Sudanese Pregnant Women in North Kordofan

Background: Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme in folate metabolism. Polymorphisms of the MTHFR gene, particularly C677T and A1298C, can reduce enzyme activity and lead to elevated homocysteine levels. This, in turn, may contribute to placental vascular disease and endothelial dysfunction, whic...

N. Suliman, K. Bakheit, K. Awadalla et al. · 0 citations

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