Formulation and In-Vitro Evaluation of Gliclazide Microspheres Using Chitosan and Sodium Alginate by Ionic Gelation Method
Gliclazide-loaded chitosan–sodium alginate microspheres were developed by ionic gelation to obtain sustained oral drug release. Six formulations (F1–F6) were prepared by varying polymer concentrations while maintaining gliclazide, sodium tripolyphosphate and Tween 80 levels constant. The microspheres were characterized...