Author

K. Almstrup

3 papers indexed here

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Open access Aug 2026

Long-read sequencing reveals pre-meiotic gene conversion in sperm

Meiotic recombination is a fundamental process that generates genetic diversity by creating new combinations of existing alleles1. Whereas crossovers in humans are well characterized2, the more frequent non-crossovers that lead to gene conversion remain challenging to study. Here we show that single high-fidelity long...

Regev Schweiger, Sang-Jin Lee, Chen-Xi Zhou et al. · Nature · 2 citations

Open access Sep 2026

Arrest of human spermatogenesis at the pachytene stage is frequently accompanied by disruption of the piRNA pathway

The data suggest that defective piRNA processing can be linked to arrest of spermatogenesis at the pachytene stage in half of the cases and establishes the piRNA pathway as a frequent and central determinant of human spermatogenic arrest with a distinctive molecular signature of impaired germ‑cell differentiation.

G. Saritaş, S. Winge, L. Sørensen et al. · Cell Death Discovery · 0 citations

Open access Aug 2026

CYP19A1 variation in healthy children: associations with breast development and pubertal gynecomastia

Background CYP19A1 encodes aromatase, the enzyme converting androgens to estrogens, thereby influencing breast tissue development in healthy children. Objective To examine associations between CYP19A1 single nucleotide polymorphisms (SNPs) and circulating estradiol (E2) and testosterone (T), the E2/T ratio and age at t...

Veronica L R Groendahl, S. Holmboe, A. Busch et al. · Endocrine Connections · 0 citations