Author

K. Afonin

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Review Open access Oct 2026

New approach methodologies in nanomedicine: bridging the gap between in silico, in vitro, and in vivo systems

The rise of nanomedicine has led to the regulatory approval of more than 80 nanoparticle (NP)-based therapeutics over the past two decades. Further advancement in the field requires a deeper understanding of the nano-bio interface of NPs, including their uptake, delivery, efficacy, toxicity, and adverse effects. Despit...

Yasmine Radwan, Laura P. Rebolledo, Elizabeth Skelly et al. · Chemical Society Reviews · 0 citations

Open access Jul 2026

Dual-Action Nucleic Acid Nanoparticles: Innate Immune Activation and Silver Nanocluster-Mediated Targeting of Intracellular Bacteria

It is confirmed that enhanced host immune activation and direct antibacterial activity result in a significant reduction of intracellular S. aureus in primary murine osteoblasts, highlighting the therapeutic potential of this platform.

Leyla Danai, Christina J. Bayard, Krishna Majithia et al. · ACS nano medicine · 0 citations