Justin Cheng

T lymphocytes and natural killer cells in myelodysplastic syndromes: function, dysfunction, and therapeutic potential

Myelodysplastic syndrome (MDS) are clonal myeloid neoplasms that cause cytopenias and can progress to acute myeloid leukemia (AML). Hypomethylating agents (HMA) are the mainstay of treatment for higher risk disease, but they achieve responses in only half of treated patients and complete remission rates are low. Severa...