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Author

Jun-Xue Wu

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Review Open access Aug 2026

Hydrogel-based strategies for periprosthetic joint infection: from osteoimmune mechanisms to clinical translation

A hydrogel-enabled perspective supports indication-driven design and more rigorous evaluation of local biomaterial strategies for PJI and indicates that hydrogels are not universally superior when mechanical support, established surgical familiarity, or long-term structural stability is required.

Chao Zhang, Rui Zhang, Yuwen Yang et al. · 0 citations
Open access Aug 2026

Biomaterial-mediated remodelling of the inflammatory microenvironment: a pH/ROS-responsive EGCG–metformin hydrogel for infected diabetic wound regeneration

In vivo, AP@EM-gel produced near-complete wound closure by day 14 and improved bacterial clearance, re-epithelialisation, collagen organisation, angiogenesis, and inflammatory resolution compared with the commercial dressing.

Rui Zhang, Suk Fei Tan, Ye Wang et al. · 0 citations

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